Life with Bacterial Secretion Systems
نویسندگان
چکیده
منابع مشابه
Life with Bacterial Secretion Systems
Mysterious organelles that span the bacterial envelope have grabbed my heart throughout my life. It was not a coincidence that bacterial secretion systems, the pivotal machinery delivering virulent determinants into infected host cells, turned out to be my central interest after switching research subjects from the bacterial flagellum, which is a locomotive organelle. The virulent type III secr...
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Numerous bacterial proteins exert their function outside the prokaryotic cell. To this end, both Gram-negative and Gram-positive bacteria have evolved specialized mechanisms to transport their proteins to the bacterial supernatant or host cell cytoplasm, so called secretion systems. These different strategies will be briefly discussed, followed by an in depth description of the Type III secreti...
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Research on specialized biological systems is often hampered by a lack of consistent terminology, especially across species. In bacterial Type IV secretion systems genes within one set of orthologs may have over a dozen different names. Classifying research publications based on biological processes, cellular components, molecular functions, and microorganism species should improve the precisio...
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The flagellum and the injectisome are two of the most complex and fascinating bacterial nanomachines. At their core, they share a type III secretion system (T3SS), a transmembrane export complex that forms the extracellular appendages, the flagellar filament and the injectisome needle. Recent advances, combining structural biology, cryo-electron tomography, molecular genetics, in vivo imaging, ...
متن کاملIdentification of Protein Secretion Systems in Bacterial Genomes Using MacSyFinder.
Protein secretion systems are complex molecular machineries that translocate proteins through the outer membrane, and sometimes through multiple other barriers. They have evolved by co-option of components from other envelope-associated cellular machineries, making them sometimes difficult to identify and discriminate. Here, we describe how to identify protein secretion systems in bacterial gen...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2016
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1005562